M-CSF | definition of M-CSF by Medical dictionary
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CSF1 A gene on chromosome 1p21-p13 that encodes colony stimulating factor 1 (macrophage), a cytokine that controls the production, differentiation and function of macrophages, and may be involved in development of the placenta.
Abbreviation for macrophage colony-stimulating factor.
macrophage colony-stimulating factor.
References in periodicals archive
Local bone injection of LPS and M-CSF
increase bone resorption by different pathways in vivo in rats.
An additional possibility is inhibition of osteoclastic resorption and remodeling of the fracture callus, as seen in mice with defective M-CSF
and RANKL signaling.
Elevate levels of its ligand M-CSF
are observed in the joints of RA patients, contributing to the development of macrophages and osteoclasts, which are the mediators of bone erosion.
00 Sensitivity, ng/L 100 1000 h TNF-[beta] (b) M-CSF
n 1/17 2/17 Average amount (SE) 12.