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M component |
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component /com·po·nent/ (kum-po´nent)
1. a constituent element or part. 2. in neurology, a series of neurons forming a functional system for conducting the afferent and efferent impulses in the somatic and splanchnic mechanisms of the body. M component an abnormal monoclonal immunoglobulin occurring in the serum in plasma cell dyscrasias, formed by proliferating concentrations of immunoglobulin-producing cells. plasma thromboplastin component (PTC) coagulation factor IX.
M component, an abnormal immunoglobulin that appears in large numbers in patients with macroglobulinemia, heavy chain disease, and multiple myeloma. component [com-po´nent] 1. a constituent element or part. 2. one part of a prosthesis system. clinical c's the three classification schemes that make up the omaha system: the problem classification scheme arranges 40 nursing diagnoses (called client problems) into four different domains; the intervention scheme assigns nursing interventions to the client problems; and the problem rating scale for outcomes assigns ratings to describe the client's problem-specific knowledge, behavior, and status at various points in the treatment process. See Appendix on the Omaha System. M component [Myeloma or Macroglobulinemia] structurally homogeneous protein in serum or urine appearing as a sharp spike in the beta or gamma globulin region on protein electrophoresis. The protein is in most cases a monoclonal immunoglobulin or heavy chain fragment, or a monoclonal immunoglobulin light chain or light chain fragment, either alone or with monoclonal immunoglobulin containing the same light chain. M components are characteristic of plasma cell dyscrasias. performance c's see performance components. plasma thromboplastin component (PTC) factor IX, one of the coagulation factors.
M component a homogeneous immunoglobulin produced by a single clone of cells in a monoclonal gammopathy. May consist of either whole immunoglobulin molecules or their subunits, e.g. light chains or heavy chains. Called also paraprotein, myeloma protein or M protein.
M component Monoclonal immunoglobulin A narrow peak or 'spike' seen on SPEP which is presumptive evidence of a monoclonal proliferation of mature B cells producing IgG, IgA or IgM Where seen Myeloma, Waldenström's
macroglobulinemia, heavy chain disease, lichen myxedematosus–a rare disease of proliferating fibroblasts. See Serum protein electrophoresis. Want to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit the webmaster's page for free fun content. |
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