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Lynen

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Ly·nen (lnn, lü-), Feodor 1911-1979.
German biochemist. He shared a 1964 Nobel Prize for research on cholesterol and fatty acid metabolism.


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1964 Konrad Bloch and Feodor Lynen received the Nobel Prize for their research on the mechanism and regulation of cholesterol and fatty-acid metabolism.
Classical work by Bloch, Cornforth and Lynen on mammalian and yeast cells in the 1950s culminated in the elucidation of the mevalonate pathway for the biosynthesis of the universal isoprenoid precursors, isopentenyl diphosphate (IPP) (7) and dimethylallyl diphosphate (DMAPP) (8) via acetyl-CoA (11), 3-hydroxy-3-methylglutaryl-CoA (10) and 5-diphospho-mevalonate (9) (for review, see Qureshi and Porter, 1981; Bach, 1995; Bloch, 1992; Bochar et al.
 
 
 
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