lymphotoxin /lym·pho·tox·in/ (lim´fo-tok″sin) tumor necrosis factor ; a lymphokine produced by activated T lymphocytes that it inhibits growth of tumors and blocks transformation of cells.
lymphotoxin [lim´fo-tok″sin]
lym·pho·tox·in (l m f -t k sn)n. A lymphokine that is toxic to certain susceptible target cells. |
lymphotoxin [lim´fo-tok″sin]
a lymphokine containing 171 amino acids, one of the tumor necrosis factors, produced by activated T lymphocytes. It inhibits the growth of tumors by causing lysis or stasis of sensitive cells, and also blocks transformation of cells. Called also tumor necrosis factor β.
lymphotoxin
a lymphokine released by antigen-stimulated lymphocytes, particularly cytotoxic T lymphocytes, and involved in target-cell lysis, as in virus-infected target cells. The killing requires cell-to-cell contact and is restricted by Class I major histocompatibility antigens. Called also tumor necrosis factor-β (TNF-β).
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