lymphoblast

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Related to Lymphoblasts: acute lymphoblastic leukemia, Lymphocytes

lymphoblast

 [lim´fo-blast]
a morphologically immature lymphocyte, once thought to represent an early stage in lymphocyte development but now known to be an activated lymphocyte that has been transformed in response to antigenic stimulation. adj., adj lymphoblas´tic.

lym·pho·blast

(lim'fō-blast),
A young immature cell that matures into a lymphocyte and is characterized by more abundant cytoplasm than in a lymphocyte, a nucleus in which the chromatin is finer than in a lymphocyte (but coarser than in a myeloblast), and one or two rather prominent nucleoli.
Synonym(s): lymphocytoblast
[lympho- + G. blastos, germ]

lymphoblast

/lym·pho·blast/ (lim´fo-blast) a morphologically immature lymphocyte, representing an activated lymphocyte that has been transformed in response to antigenic stimulation.lymphoblas´tic

lymphoblast

(lĭm′fə-blăst′)
n.
A dividing cell that gives rise to a mature lymphocyte.

lym′pho·blas′tic adj.

lymphoblast

[lim′fəblast′]
a large, immature cell that develops into a lymphocyte after an antigenic or mitogenic challenge. lymphoblastic, adj.

lym·pho·blast

(lim'fō-blast)
An immature cell that matures into a lymphocyte and is characterized by more abundant cytoplasm than in a lymphocyte, a nucleus in which the chromatin is finer than in a lymphocyte (but coarser than in a myeloblast), and one or two prominent nucleoli.
Synonym(s): lymphocytoblast.
[lympho- + G. blastos, germ]

lymphoblast

An immature LYMPHOCYTE.

lymphoblast

the immature, nucleolated precursor of the mature lymphocyte. Called also large lymphocyte.
References in periodicals archive ?
Cytogenetics and molecular genetics of T-cell acute lymphoblastic leukemia: from thymocyte to lymphoblast.
Haematogones show continuous and complete maturation spectr um on immunophenotyping, lack aberrant or asynchronus antigen expression while lymphoblasts from ALL deviate from the normal B-lineage maturation spectrum by exhibiting maturation arrest, over or under antigenic expression, asynchronus antigen expression or expression of myeloid associated antigens.
Since the lymphoblasts can be distinguished and separated from the others by their distance in the feature space, we considered lymphoblast as the only class in the training set and all the remaining objects are considered as the background.
As the lymphoblasts do not mature, they can't do the work of normal white blood cells and fight infection.
Microscopically, caseated lymph nodes depicted early caseation intermingled with lymphoblasts and lymphocytes.
This is illustrated by a recent report suggesting that altered DNA methylation of the regulatory region of a gene encoding the enzyme monoamine oxidase A (MAOA) in white blood cells known as lymphoblasts is associated with alcohol dependence in female but not in male subjects (Philibert et al.
These antigen stimulate T-cells, transform into lymphoblasts and populate in different primary and secondary lymphoid organs such as spleen, MALT (mucosal associated lymphoid tissue) etc.
After studying two mouse models of Huntington's disease as well as lymphoblasts (white cells) from people with the disease, she and her team found that the mutated huntingtin protein was sabotaging the cell's garbage-collecting efforts.
Hematogones may morphologically resemble the neoplastic lymphoblasts of precursor B cells of acute lymphoblastic leukaemia (ALL) and their immune-phenotype also has features in common with neoplastic lymphoblasts (5,6).