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The formation of lymphatics (lymphatic vessels).
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Tumour cell-derived WNT5B modulates in vitro lymphangiogenesis via induction of partial endothelial-mesenchymal transition of lymphatic endothelial cells.
Eiger will continue to develop ubenimex for lymphedema based on its distinct mechanism of action impacting lymphangiogenesis as published in Science Translational Medicine (Tian et al, May 2017).
2) It is declared that based on angiogenesis and/or lymphangiogenesis induction of tumor cells, the metastases are different.
20] STAT3 also could bond with the promoter of vascular endothelial growth factor, promoting the angiogenesis and lymphangiogenesis of HCC and adjacent tissues.
Expression of endocan has been described to a great extent to be strongly up-regulated in the presence of proangiogenic molecules such as VEGF-A and VEGF-C which are critical mediators involved in angiogenesis, lymphangiogenesis, and cancer progression.
Dry eye predisposes to corneal neovascularization and lymphangiogenesis after corneal injury in a murine model.
Some researchers suggest that the B7-H3 signaling system is one of efficient pathway in regulating lymphangiogenesis.
As a result, inhibition of the kinase disrupts lymphangiogenesis.
Soengas (CNIO, Spain) show that CQ affects lymphangiogenesis even more than angiogenesis.
Ovarian cancer-associated fibroblasts contribute to epithelial ovarian carcinoma metastasis by promoting angiogenesis, lymphangiogenesis and tumor cell invasion," Cancer Letters, vol.