For additional information on Lupron Depot-PED for the treatment of central precocious puberty, visit www.
Use for Lupron Depot-PED (leuprolide acetate for depot suspension)
Children should not receive any formulation of Lupron Depot-PED if they have experienced any type of allergic reaction to Lupron Depot-PED or similar drugs.
Females who are or may become pregnant should not receive any formulation of Lupron Depot-PED.
During the first weeks of Lupron Depot-PED treatment, signs of puberty, such as vaginal bleeding, may occur.
The initial response to Lupron Depot-PED should be monitored, as well as the continued response during treatment, as clinically needed.
The most common side effects for any GnRH agonist, including Lupron Depot-PED, are injection site reactions/pain including abscess, general pain, headache, fluctuating emotions, and hot flushes/sweating.
The most frequent adverse reactions in Lupron Depot-PED studies were pain; acne; injection site reactions, including pain, swelling and abscess; rash, including a painful rash with fever, blisters/sores, and facial swelling; vaginitis/vaginal bleeding/vaginal discharge; increased weight; and altered mood.