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low-molecular weight heparin |
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low-molecular weight heparin Enoxaparin/Lovenox®, dalteparin, fraxiparin Pharmacology A heparin with advantages over unfractionated heparin, which blocks thrombosis earlier in the coagulation cascade than conventional heparin
by inhibiting factor Xa; it less likely to cause thrombocytopenia or thrombotic thrombocytopenia syndrome Indications DVT. See Deep vein thrombosis. How to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit webmaster's page for free fun content. |
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| In their study, the researchers administered a fixed dose of plain heparin by syringe to half of the 708 volunteers and a low-molecular weight heparin, also by syringe, to the others. Using Premier's Perspective(TM) database, researchers from Premier compared actual inpatient treatments to evidence-based prophylaxis guidelines involving the use of unfractionated (UH) and low-molecular weight heparin (LMWH) and compression devices put forth by the American College of Chest Physicians for several categories of medical and surgical diagnoses. Other known clinical agents, such as direct thrombin inhibitors and low-molecular weight heparin are not known to have effects across all three cascades, nor have these compounds shown any anti-platelet effects. |
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