Lou Gehrig's disease

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amyotrophic lateral sclerosis

a progressive neurologic disease characterized by degeneration of cell bodies of the lower motor neurons in the gray matter of the anterior horns of the spinal cord, some brainstem motor neurons, and the pyramidal tracts. Called also Lou Gehrig's disease.

The disease presents in adulthood, usually between the ages of 40 and 70, and affects men two to three times more often than women. The initial symptom is weakness of skeletal muscles, especially in the limb. As the disease progresses the patient has difficulty swallowing and talking, with dyspnea as the accessory muscles of respiration are affected. Eventually muscles atrophy and the patient becomes a functional quadriplegic. Mentation is not affected, so that the patient remains alert and aware of functional loss and the inevitable outcome. Although there may be periods of remission, the disease usually progresses rapidly, with death in 2 to 5 years. The cause of ALS is not known and there is no cure. Treatment is intended to provide symptomatic relief, prevent complications, and maintain optimal function as long as possible.
Patient Care. For the most part, ALS patients are cared for at home and are hospitalized only for diagnosis, when severe dysphagia demands an esophagostomy or gastrostomy for feeding, or when medical treatment is necessary for acute respiratory problems.

Intervention is planned and implemented according to each patient's needs at specific times during the course of the illness. In general, the major problems encountered are those related to (1) dysphagia and the need to meet nutritional requirements and avoid aspiration, (2) dyspnea and maintenance of blood gases within normal range, (3) aphasia and impaired verbal communication, (4) weakness, impaired mobility, and activity intolerance, (5) constipation, (6) pain and discomfort due to muscle cramps, and (7) alteration in self-concept and body image.

The patient and family also will need assistance in managing home care, coping with the effects of the illness, and maintaining optimal functioning in the patient. Community health nurses and home health care professionals and paraprofessionals should be available to provide a variety of services including physical therapy, occupational therapy, social services, mental health care, and medical and nursing care.

A resource agency that can provide assistance and information to ALS patients and their families is the Amyotrophic Lateral Sclerosis Association, 21021 Ventura Blvd., Suite 321, Woodland Hills, CA 91364-2206, (800) 782–4747; http://www.alsa.org.

Lou Gehrig's disease

(lo͞o′ gĕr′ĭgz)

Lou Gehrig's disease

Lou Gehrig's disease

A popular term in the USA for AMYOTROPHIC LATERAL SCLEROSIS. Lou Gherig (1904–41) was a baseball player for the Yankees of countrywide fame and popularity who, to the distress of all who knew him, began to develop signs of ALS in 1938.

Patient discussion about Lou Gehrig's disease

Q. What are the presenting signs of ALS? Are the upper or lower extremeties affected initialilly?

A. The most common presenting sign of ALS is asymmetric limb weakness, usually starting with the hands (problems with pinching, writing, holding things etc.) shoulders (lifting arms above head etc.) or legs (problems walking).

Other presenting signs may be problems with speaking or swallowing, although these are less common.

You may read more here:

Q. hola amigos como estan yo estranando al amor de mi via que es monica la amo mchoy la estrano bastante hola soy un tipo muy feliz ya encontre el amor de mi vida nos casamos en diciembre tenemos muchos suenos ,un camino muy largo que recorrer pienso entregarme por completo al amor y dedicarnos el uno para el hotro ,yon amo ami baby estoy muy enamorado ella lo sabe es mi baby te amo mi gatita bebe

A. ¿Cuál es la pregunta?

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References in periodicals archive ?
1 -- color) Chris Taylor, center, who lives with parents Ernest and Gwen, is working on a new novel despite Lou Gehrig's disease.
The scientific world is a step closer to finding a cure for Lou Gehrig's disease because of the people who support and participate in the 146 Walks held in the United States.
The bulk of proceeds will help offset medical bills and daily living expenses for Johnson, a 36-year-old single father who is diagnosed with amyotrophic lateral sclerosis, also known as Lou Gehrig's disease.
Most people have heard of Lou Gehrig's disease, but they really don't know how ugly it is,'' he said.
Nobody claims riluzole can cure amyotrophic lateral sclerosis (ALS), the medical name for Lou Gehrig's disease.
Kevorkian, 70, still could get a life term at sentencing April 14 for the death of 52-year-old Thomas Youk, who suffered from Lou Gehrig's disease.
The eStore will produce additional monies that will go toward research into finding a cure for Lou Gehrig's disease and patient services that will help people with ALS and their families live with the disease.
Mark Reiman, who at 44 seems too young and full of life to be struck with the as-yet incurable Lou Gehrig's disease, set out from his home north of Seattle five months ago with a dream to sing the anthem in all 30 major-league parks by season's end.
ALS, commonly known as Lou Gehrig's disease or Motor Neuron Disease, is a progressive neurodegenerative disease that attacks motor neurons in the brain (upper motor neurons) and spinal cord (lower motor neurons).
Martinou and his colleagues suggest that their finding might provide insights into degenerative diseases of the nervous system, such as Lou Gehrig's disease and Huntington's disease.
Dyer died of amyotrophic lateral sclerosis, commonly known as Lou Gehrig's disease.
The prevalence of amyotrophic lateral sclerosis (ALS), or Lou Gehrig's disease, was up to 100 times higher among the Chamorro inhabitants of the islands than among the people living in developed countries.