losartan

losartan /lo·sar·tan/ (lo-sahr´tan) an angiotensin II receptor antagonist, used as an antihypertensive; used as the potassium salt.

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losartan,

an antihypertensive.

indications It is used to treat hypertension, either alone or in combination with other drugs.

contraindications Factors that prohibit the use of this drug are known hypersensitivity to tramadol and second- and third-trimester pregnancy.

adverse effects Life-threatening effects are cerebrovascular insult and myocardial infarction. Other adverse effects are anxiety, confusion, abnormal dreams, migraine, tremor, vertigo, task perversion, angina pectoris, second-degree atrioventricular block, hypotension, blurred vision, burning eyes, conjunctivitis, anorexia, constipation, dry mouth, flatulence, gastritis, vomiting, impotence, nocturia, urinary frequency, urinary tract infection, anemia, alopecia, dermatitis, dry skin, flushing, photosensitivity, rash, pruritus, sweating, gout, cramps, myalgia, pain, stiffness, congestion, dyspnea, and bronchitis. Common side effects are dizziness, insomnia, arrhythmias, diarrhea, dyspepsia, cough, and upper respiratory infection.

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losartan

Cozaar^® Pharmacology A sartan which blocks angiotensin II–A-II from binding to AT₁, ↓ proteinuria and filtration fraction, inhibits secretion of aldosterone by the adrenal cortex, and ↑ uric acid excretion; in Pts with CHF, losartan ↓ afterload, ↑ cardiac output–effects shared by ACE inhibitors—and prevent left ventricular hypertrophy Side effects Vertigo. See Angiotensin II receptor antagonist, ELITE.