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lopinavir

   Also found in: Wikipedia 0.02 sec.
lopinavir /lo·pin·a·vir/ (lo-pin´ah-vir) an antiviral HIV protease inhibitor, used with ritonavir in the treatment of HIV infection.
lopinavir
[lopin′ävir]
an HIV protease inhibitor, an orally administered antiviral agent used in combination with ritonavir in the treatment of human immunodeficiency virus infection.


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The recent intriguing results from a couple of small studies using lopinavir and low-dose ritonavir (Kaletra) monotherapy may result in a new paradigm shift.
The FDA approves Kaletra, a combination pill containing 2 PIs, lopinavir and ritonavir (Norvir), where a small dose of ritonavir is included to boost levels of lopinavir.
assistant trade representative, quoted in The Wall Street Journal, September 5, 2003 on Brazil's plan to use compulsory licensing to authorize government importing of three generic drugs for HIV (efavirenz, lopinavir, and nelfinavir) until it can make sufficient quantities domestically, unless the patent holders will give Brazil a larger discount.
 
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