lomefloxacin


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antibiotic

 [an″te-, an″ti-bi-ot´ik]
1. destructive of life.
2. a chemical substance produced by a microorganism that has the capacity, in dilute solutions, to kill other microorganisms or inhibit their growth. Antibiotics that are sufficiently nontoxic to the host are used as chemotherapeutic agents in the treatment of infectious diseases. See also antimicrobial agent.
antineoplastic a's (antitumor a's) a class of antineoplastic agents that apparently affect the function or the synthesis, or both, of nucleic acids and thus are cell cycle nonspecific. See also antineoplastic therapy.
broad-spectrum antibiotic one that is effective against a wide range of bacteria, both gram-positive and gram-negative.
β-lactam antibiotic any of a group of antibiotics, including the cephalosporins and the penicillins, whose chemical structure contains a β-lactam ring.

lomefloxacin

/lo·me·flox·a·cin/ (lo″mĕ-flok´sah-sin) a broad-spectrum antibiotic effective against a wide range of aerobic gram-negative and gram-positive organisms; used as the hydrochloride salt.

lomefloxacin

[lo′mĕflok′säsin]
a broad-spectrum antibiotic effective against a wide range of aerobic gram-negative and gram-positive organisms, used as the hydrochloride salt.

lomefloxacin

Maxaquin® Infectious disease A broad-spectrum quinolone for treating uncomplicated and complicated UTIs, prophylaxis of bacterial infection in posttransurethral surgery and transrectal prostate biopsy, for acute bacterial exacerbation of chronic bronchitis gram-negative bacilli, staphylococci. See Fluoroquinolone.
References in periodicals archive ?
The retention times for ciprofloxacin and lomefloxacin were ~12 and 16 min, respectively.
We also thank Bayer Pharmaceuticals for the supply of ciprofloxacin and the Shionogi Pharmaceutical Company, Osaka, Japan, for the supply of lomefloxacin.
38] Norfloxacin, lomefloxacin, and ofloxacin do not cause this problem.
Staphylococcus aureus is resistant to Gentamicin, Cotrimoxazole, and Lomefloxacin.
Ciprofloxacin inhibits theophylline clearance by about 30%,(11)(16) whereas norfloxacin, ofloxacin, and lomefloxacin usually produce a minimal effect.
For GNB, Ceftazidime, Ciprofloxacin, Lomefloxacin, Gentamicin and Netilline and for GPB, Cephalexin, Linezolid, Gentamicin, Amoxyclav and Tetracycline appear to be the first line antibiotic to treat CSOM.
Statistically significant difference was found in the resistance pattern of MBL positive and negative isolates for amikacin, netilmicin, cefepime, ceftazidime, ceftriaxone, ciprofloxacin and lomefloxacin (P<0.
Various antimicrobial agents ([micro]g) used were amikacin (30), gentamicin (10), tobramycin (10), ceftazidime (30), ceftriaxone (30), ceftizoxime (30), cefoperazone (75), carnbenicillin (100), piperacillin (100), Ticarcillin (75), ciprofloxacin (5), lomefloxacin (10) and imipenem (10) (Hi-media, Mumbai, India).
67% to lomefloxacin, azithromycin to 50%, and 100% isolates were showed resistant to ciprofloxacin and cloxacillin.
patents for single-isomer versions of FDA-approved drugs: oxybutynin to treat urinary incontinence; doxazosin to treat benign prostatic hyperplasia; and lomefloxacin, a broad-spectrum antibiotic for the treatment of urinary infections.
The patents cover the use of purified versions of: oxybutynin, a leading treatment for urinary incontinence; doxazosin, a treatment for benign prostatic hyperplasia; and lomefloxacin, a treatment for bacterial infections.