lomefloxacin


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antibiotic

 [an″te-, an″ti-bi-ot´ik]
1. destructive of life.
2. a chemical substance produced by a microorganism that has the capacity, in dilute solutions, to kill other microorganisms or inhibit their growth. Antibiotics that are sufficiently nontoxic to the host are used as chemotherapeutic agents in the treatment of infectious diseases. See also antimicrobial agent.
antineoplastic a's (antitumor a's) a class of antineoplastic agents that apparently affect the function or the synthesis, or both, of nucleic acids and thus are cell cycle nonspecific. See also antineoplastic therapy.
broad-spectrum antibiotic one that is effective against a wide range of bacteria, both gram-positive and gram-negative.
β-lactam antibiotic any of a group of antibiotics, including the cephalosporins and the penicillins, whose chemical structure contains a β-lactam ring.

lomefloxacin

/lo·me·flox·a·cin/ (lo″mĕ-flok´sah-sin) a broad-spectrum antibiotic effective against a wide range of aerobic gram-negative and gram-positive organisms; used as the hydrochloride salt.

lomefloxacin

[lo′mĕflok′säsin]
a broad-spectrum antibiotic effective against a wide range of aerobic gram-negative and gram-positive organisms, used as the hydrochloride salt.

lomefloxacin

Maxaquin® Infectious disease A broad-spectrum quinolone for treating uncomplicated and complicated UTIs, prophylaxis of bacterial infection in posttransurethral surgery and transrectal prostate biopsy, for acute bacterial exacerbation of chronic bronchitis gram-negative bacilli, staphylococci. See Fluoroquinolone.
References in periodicals archive ?
In a microcentrifuge tube, 30 [micro]L of the working solution of lomefloxacin was added to 50 [micro]L of the diluted urine.
Statistically significant difference was found in the resistance pattern of MBL positive and negative isolates for amikacin, netilmicin, cefepime, ceftazidime, ceftriaxone, ciprofloxacin and lomefloxacin (P<0.
Various antimicrobial agents ([micro]g) used were amikacin (30), gentamicin (10), tobramycin (10), ceftazidime (30), ceftriaxone (30), ceftizoxime (30), cefoperazone (75), carnbenicillin (100), piperacillin (100), Ticarcillin (75), ciprofloxacin (5), lomefloxacin (10) and imipenem (10) (Hi-media, Mumbai, India).
With the transfer of production licenses and manufacturing registration numbers, Jade Pharmaceutical will focus on selling into the China pharmaceutical products market with four new drugs (Marine and Sodium Chloride Injection, Lomefloxacin Aspartate Injection, Lysine Hydrochloride and Glucose Injection, Omeprazole Sodium for Injection) and two antibiotic medicines, Roxithromycin and Levofloxacin.
In Japan, three carbapenems (imipenem, panipenem, and meropenem) and at least nine fluoroquinolones (enoxacin, fleroxacin, norfloxacin, ofloxacin, ciprofloxacin, lomefloxacin, tosufloxacin, sparfloxacin, and levofloxacin) are used as first-line drugs in every clinical setting, although use of these drugs is restricted in many western countries, including the United States.
As part of the initial phase of the cooperation, the parties will negotiate a mutually beneficial Product Licensing Agreement (PLA) in which JMB agrees to transfer its four new drugs (including Marine and Sodium Chloride Injection, Lomefloxacin Aspartate Injection, Lysine Hydrochloride and Glucose Injection, Omeprazole Sodium for Injection) and two generic medicine (including Roxithromycin capsule and Levofloxacin capsule) production licenses and manufacturing registration numbers to JJB.
In a clinical study (n=48), TEQUIN demonstrated a lower potential for producing delayed photosensitivity skin reactions than ciprofloxacin or lomefloxacin, and was comparable to placebo in causing these same reactions.
patents for single-isomer versions of FDA-approved drugs: oxybutynin to treat urinary incontinence; doxazosin to treat benign prostatic hyperplasia; and lomefloxacin, a broad-spectrum antibiotic for the treatment of urinary infections.