They cautioned that a recent study suggested that people with a history of lobar hemorrhage
might be at particular risk from statin therapy Since their study "could not test this important subset" of stroke survivors, clinicians should remain cautious about prescribing statins for such patients, the researchers said.
With cerebral amyloid angiopathy, there is progressive amyloid deposition restricted to small- to medium-sized vessels of the brain that leads to fibrinoid necrosis and vascular frailty, and there is often associated diffuse multifocal white matter disease, and symptomatic lobar hemorrhage
The 1999 American Heart Association management guidelines for ICH recommend a computed tomography (CT) scan to diagnose ICH, no use of steroids, no surgical evacuation for patients with a Glasgow Coma Score of 4 or less or IVH less than 3 cm on CT, and consideration of surgical evacuation in "young patients with moderate to large lobar hemorrhage
with clinical deterioration.
The blood vessels become brittle which can lead to recurrent strokes and potentially devastating lobar hemorrhages
in the brain.