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lithocholic acid

   Also found in: Acronyms, Encyclopedia 0.03 sec.
lithocholic acid 
a secondary bile acid formed by dehydroxylation of chenodeoxycholic acid in the intestine; some is reabsorbed and forms conjugates with glycine and taurine.

lithocholic acid
the product of bacterial metabolism of bile acids in the intestine. Insoluble and not reabsorbed.


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The non-steroidal ligands may be important tools for studying the pharmacology of the receptor, because they may not have the property of bile acids and are not metabolized to form harmful lithocholic acid (Fischer et al.
After excretion into the bile, the primary bile acids CA and CDCA are partly 7[alpha]-dehydroxylated in the intestine by bacterial enzymes to create the secondary bile acids, deoxycholic acid and lithocholic acid, respectively (Fig.
 
 
 
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