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lissencephaly

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lissencephaly /lis·sen·ceph·a·ly/ (lis″en-sef´ah-le) agyria.lissencephal´ic
lissencephaly.
See agyria .

lissencephaly [lis″en-sef´ah-le]
agyria. adj., adj lissencephal´ic.

lissencephaly
a malformation in which the gyri of the cerebral cortex are not normally developed. In dogs it has been associated with behavioral abnormalities, visual deficits, ataxia and seizures. Called also agyria.

lissencephaly
Neurology A brain malformation that is isolated or associated with other syndromes–eg, Miller-Dieker syndrome, Norman-Roberts syndrome, characterized by absence–agyria or incomplete development–pachygyria of cerebral gyri Clinical Microcephaly, seizures, profound mental retardation, feeding difficulties, growth retardation, impaired motor activity


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Byline: ANI Washington, Sep 7 (ANI): By using protease inhibitors, researchers at the University of California-San Francisco (UCSF) have restored to normal levels a key protein that is involved in early brain development, and causes the rare brain disorder lissencephaly.
Rebecca, from Ingleby Barwick, was diagnosed with lissencephaly when she was just 10 weeks old, which means she has severe delays in her development and struggles with rolling, sitting and balancing.
As Lissencephaly is such a rare condition - affecting just four children born every year in the UK - there is no dedicated charity support available like there is for other illnesses such as cancer.
 
 
 
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