insulin lispro(redirected from Lispro)
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A rapid-acting insulin analog whose amino acid sequence differs from that of human insulin by a reversal in the order of lysine and proline in the B chain, used in the treatment of type 1 and type 2 diabetes.
a pancreatic hormone.
indications It is used to treat ketoacidosis types I and II and types 1 and 2 diabetes mellitus.
contraindications Known hypersensitivity to this drug or to protamine prohibits its use.
adverse effects Anaphylaxis is a life-threatening effect of this drug. Other adverse effects include blurred vision, dry mouth, flushing, rash, urticaria, warmth, lipohypertrophy, swelling, redness, and rebound hyperglycemia (the Somogyi effect). Lipodystrophy and hypoglycemia are common side effects.
A synthetic insulin with a very rapid onset and short duration of action. Diabetic patients typically use it immediately before meals to prevent postprandial hyperglycemia. Its absorption is more rapid than regular insulin. It is made by reversing the amino acids lysine and proline in the beta chain of the insulin polypeptide (hence its name lispro).
See also: insulin