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lipoatrophic diabetes

   Also found in: Wikipedia 0.03 sec.
lipoatrophic diabetes
[lip′ō·atrof′ik]
an inherited disease characterized by a total loss of subcutaneous body fat, insulin-resistant diabetes mellitus, acanthosis nigricans, hypermetabolism, hepatomegaly, and hypertrophied musculature. It is associated with a disorder of the hypothalamus that results in excessive blood levels of growth hormone and adrenocorticotropic-releasing hormones. Also called congenital total lipodystrophy.


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