Limited scleroderma

Limited scleroderma

A subtype of systemic scleroderma with limited skin involvement. It is somestimes called the CREST form of scleroderma, after the initials of its five major symptoms.
Mentioned in: Scleroderma
References in periodicals archive ?
Runner, R-Lancaster, has limited scleroderma, an autoimmune disease that affects the body's connective tissue.
Risk factors for PAH include underlying connective tissue disease, especially limited scleroderma and mixed connective tissue disease, a family history of PAH, the presence of congenital heart disease, and environmental factors such as exposure to anorexigens.
First, the skin involvement in diffuse scleroderma can occur anywhere, whereas in limited scleroderma the telangiectasias involve only the face, feet, forearms, and hands, with skin thickening limited to the face and hands (4, 5).
Steen noted a prospective trial at the University of Pittsburgh in which 26 women had limited scleroderma and 41 pregnancies and 33 women with diffuse scleroderma had 50 pregnancies from 1987 to 1996.
Systemic scleroderma can be classified into two forms, depending on the degree of skin involvement: limited scleroderma - often referred to as CREST - and diffuse scleroderma.