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limb-girdle muscular dystrophy
(redirected from Limb-girdle)

   Also found in: Dictionary/thesaurus, Wikipedia 0.01 sec.
limb-girdle muscular dystrophy
n.
A progressive inherited disorder that usually begins in preadolescents and is characterized by symptoms similar to those present in facioscapulohumeral muscular dystrophy with the pelvic girdle often being the most severely affected part.

Limb-girdle muscular dystrophy (LGMD)
An autosomal recessive form of muscular dystrophy that appears anywhere from late childhood to middle age and is characterized by progressive muscular weakness beginning either in the shoulder or pelvic girdle; the disease usually progresses slowly with cardio-pulmonary complications in the later stages

limb-girdle muscular dystrophy
Etymology: AS, lim, limb, gyrdel
a form of muscular dystrophy transmitted as an autosomal-recessive trait. The characteristic weakness and degeneration of the muscles begins in the shoulder girdle or in the pelvic girdle. The condition is progressive, regardless of the area in which it is first manifest. Kinds of limb-girdle muscular dystrophy are Erb's muscular dystrophy, Leyden-Möbius muscular dystrophy.


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Zoe Hallam, 18, who has limb-girdle muscular dystrophy, said: "In a process that is already complicated for any student, the additional restrictions placed on disabled people can make it a real challenge to go to university.
Dysferlinopathy is a rare form of limb-girdle muscular dystrophy where muscle weakness and atrophy is caused by deficiency of the dysferlin protein.
Byline: ANI Washington, April 16 (ANI): Researchers from the University of Florida (UF), Nationwide Children's Hospital in Columbus, Ohio, and The Ohio State University have safely transferred a gene to produce a protein necessary for healthy muscle fibre growth into three teenagers with limb-girdle muscular dystrophy.
 
 
 
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