Clear Cell (redirected from Light Cell)

clear cell (klîr)

n.

A cell, especially a neoplastic one, containing abundant glycogen or other material that is not stained by hematoxylin or eosin, so that the cytoplasm appears clear histologically.

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clear cell

Etymology: L, clarus + cella, storeroom

1 a type of cell found in the parathyroid gland that does not take on a color with the ordinary tissue stains used for microscopic examination.

2 the principal cell of most renal cell carcinomas and occasionally of ovarian and parathyroid tumors.

3 a specific type of epidermal cell, probably of neural origin, that has a dark-staining nucleus but clear cytoplasm with hematoxylin and eosin stain.

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Clear Cell

A finely vacuolated, cholesterol-filled cell with central dark nuclei, which is arranged in clusters and located in the midzone or zona fasciculata of the adrenal cortex. Clear cells are the major reservoir for glucocorticoid and sex hormone production when the adrenal gland is stressed