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ligand |
Also found in: Dictionary/thesaurus, Encyclopedia, Wikipedia, Hutchinson | 0.01 sec. |
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ligand /li·gand/ (li´gand) (lig´and) an organic molecule that donates the necessary electrons to form coordinate covalent bonds with metallic ions. Also, an ion or molecule that reacts to form a complex with another molecule.
ligand [lig′ənd, lī′gənd] Etymology: L, ligare, to bind 1 a molecule, ion, or group bound to the central metal atom of a chemical compound, such as the oxygen molecule in oxyhemoglobin, which is bound to the central iron atom. 2 an organic molecule attached to a specific site on a cell surface or to a tracer element. The binding is reversible in a competitive binding assay. It may be the analyte or a cross-reactant. Examples include vitamin B12, a ligand with intrinsic factor as the binding protein, and various antigens, which are ligands with antibody-binding proteins. ligand (līg n 1. a molecule, ion, or group bound to the central atom of a chemical compound, such as the oxygen molecule in hemoglobin, which is bound to the central iron atom. 2. an organic molecule attached to a specific site on a surface or to a tracer element. ligand an organic molecule that donates the necessary electrons to form coordinate covalent bonds with metallic ions. Also, an ion or part of a molecule that specifically binds to form a complex with another molecule. How to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit webmaster's page for free fun content. |
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Ligand has been a pioneer in the discovery of compounds that act as ligands for the nuclear receptor RXR with distinct selectivity and has termed these novel compounds &uot;rexinoids. This study is the first evidence suggesting that Targretin and other RXR ligands activate a genetic pathway that may provide a novel approach for breast cancer therapy. |
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