ionotropic

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ionotropic

(ī″ŏn-ŏ-trō′pĭk) [″ + ″]
Having an influence on glutamate-gated cell surface receptors, i.e., on cell membrane channels that open or close in the presence of ions.
References in periodicals archive ?
They noted a protein sequence on the bacteria that is remarkably similar to the sequence of a group of ligand-gated ion channels in the human brain.
Over the last two decades, numerous studies have shown that alcohol affects many different types of ion channels, including ligand-gated ion channel receptors (Narahashi et al.
The nAChRs belong to the cys-loop superfamily of ligand-gated ion channels, which also includes [lambda]-aminobutyric acid (GABA)-gated Cl- channels, glycine receptors, glutamate-gated Cl- channels, and 5-hy droxytryptamine type 3 (5-HT3) receptors (Lester et al.
Evolutionary relationship of the ligand-gated ion channels and the avermectin-sensitive, glutamate- gated chloride channels, J.
The IonWorks Barracuda System can screen both voltage-gated and rapidly-desensitizing ligand-gated ion channels due to the unique design of the Patch Plate Consumable and an electrode plate that enables researchers to add compound while recording.
BioFocus DPI will utilize Cellectricon's Dynaflow(R)HT, a fully automated patch clamp (APC) system, to further increase its electrophysiology-based screening capacity, particularly for fast ligand-gated ion channels.
DF-48 is optimized for ligand-gated ion channels and has been beta-tested by GSK.
PRODUCT OVERVIEW II-20 Ion Channel Modulators: An Introduction II-20 Biological Significance of Ion Channels II-20 Ion Channel Modulators as an Option for Treating Diseases II-20 Types of Ion Channels II-21 Voltage-Gated Ion Channels II-21 Extracellular Ligand-gated Ion Channels II-22 Intracellular Ligand-gated Ion Channels II-24 5.
PRODUCT OVERVIEW II-7 Ion Channel Modulators: An Introduction II-7 Biological Significance of Ion Channels II-7 Ion Channel Modulators as an Option for Treating Diseases II-7 Types of Ion Channels II-8 Voltage-Gated Ion Channels II-8 Extracellular Ligand-gated Ion Channels II-9 Intracellular Ligand-gated Ion Channels II-11
PRODUCT OVERVIEW II-7Ion Channel Modulators: An Introduction II-7Biological Significance of Ion Channels II-7Ion Channel Modulators as an Option for Treating Diseases II-7Types of Ion Channels II-8Voltage-Gated Ion Channels II-8Extracellular Ligand-gated Ion Channels II-9Intracellular Ligand-gated Ion Channels II-11