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Leydig cell hyperplasia

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Leydig cell hyperplasia
Endocrinology Autonomous hyperplasia and hyperfunction of Leydig cells Etiology Activating mutation of LH receptor gene Clinical Precocious puberty Management Orchidectomy


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Occasionally, true Leydig cell hyperplasia or at least relative prominence of Leydig cells in an atrophic testis may suggest a small Leydig cell tumor, but these are typically multifocal and separated by seminiferous tubules, a setting that should always favor a nonneoplastic proliferation.
Leydig cell tumor differs from Leydig cell hyperplasia by being solitary, whereas nodular Leydig cell hyperplasia is characteristically multifocal.
 
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