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Lewy bodies |
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Lewy bodies [lā′wē, lo̅o̅′ē] Etymology: Frederick H. Lewy, German neurologist, 1885-1950 concentric spheres found inside vacuoles in midbrain and brainstem neurons of patients with idiopathic parkinsonism, Alzheimer's disease, and other neurodegenerative conditions. How to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit webmaster's page for free fun content. |
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Chandler had been suffering from a degenerative brain disorder known as Lewy body disease, said Tom Johnson, who succeeded Chandler as publisher. The new mutation, E46K, of alpha-synuclein causes Parkinson and Lewy body dementia. The false-positive rate of CSF protein 14-3-3 for CJD can be as high as 12%, however, with other causes including vascular disorders, infectious encephalitis, anoxia, malignancy, and even Alzheimer's, Lewy body, and frontotemporal dementias (15,17-21). |
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