Lewy body


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Lewy body

(loo-wē)
[Frederic H. Lewy, Ger. neurologist, 1885–1950]
A neuronal cell with pigmented inclusion bodies. They are found in the brain in the substantia nigra and locus ceruleus, esp. in patients with a unique form of dementia with some Parkinsonian features, known as "dementia with Lewy bodies."
References in periodicals archive ?
Professor McKeith is founding president of the Lewy Body Society, an organisation set up to support research into the disease, raise awareness and to educate the public, medical professionals and those in healthcare decision-making positions.
It gets rid of alpha synuclein and tau in a number of movement disorders, such as Parkinson's disease as well as Lewy body dementia.
The recent National Institute on Aging-Alzheimer's Association (NIA-AA) revision of criteria for the pathologic diagnosis of AD recommends a minimum of 13 histologic sections to evaluate for Alzheimer disease neuropathologic change (ADNC), Lewy body disease (LBD), vascular brain injury, microvascular lesions, and hippocampal sclerosis.
The investigators used both clinical diagnoses and histopathology to identify patients as having Alzheimer's disease without Lewy bodies (244), Alzheimer's with Lewy bodies (224), pure Lewy body dementia (91), or Parkinson's dementia without Alzheimer's neuropathology (81).
Remembrances to Lewy Body Dementia Association or St.
Twenty-seven European and North American academics and practitioners contribute 19 chapters offering mental health professionals as well as general practitioners and students an up-to-date discussion of new evidences from basic and clinical sciences concerning four major dementing illnesses likely to be encountered in a daily practice: Alzheimer's disease, vascular dementia, Lewy body disease, and frontotemporal dementia.
Of these, 14 developed Parkinson's disease, and seven developed Lewy body dementia, marked by the appearance of Lewy bodies--abnormal protein deposits--in the brain.
Accuracy of the clinical diagnoses of Lewy body disease, Parkinson disease, and dementia with Lewy bodies: a clinicopathologic study.
The false-positive rate of CSF protein 14-3-3 for CJD can be as high as 12%, however, with other causes including vascular disorders, infectious encephalitis, anoxia, malignancy, and even Alzheimer's, Lewy body, and frontotemporal dementias (15,17-21).
Included illnesses are Alzheimer's, stroke and other vascular dementias, Parkinson's disease, frontal temporal dementias, traumatic brain injury, Huntington's disease, multiple sclerosis, Lewy body dementias, amyotrophic lateral sclerosis, Creutzfeldt-Jakob disease, HIV dementia and those caused by brain tumors, and other disorders.
Jack Burkitt died aged 77 of Lewy body disease on September 12 at his home in West Yorkshire.