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Lewisite

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lewisite
[lo̅o̅′isīt]
Etymology: Winford L. Lewis, American chemist, 1878-1943
2-chlorovinyl arsine, a poisonous blister gas used in World War I that causes irritation of the lungs, dyspnea, damage to the tissues of the respiratory tract, tears, and pain.
Lewisite
An organoarsenic compound developed as a vesicating chemical weapon, and manufactured by the US and Japan; it causes chemical burns or blisters of the skin and mucosa—e.g., conjunctiva, lacrimation, and pulmonary irritation and erosion— and liver necrosis
lewisite
an arsenical mustard; used as a war gas. The possibility of arsenic poisoning in animals by this means now seems remote. The chief claim for the product in recent times is the production of an antidote which has come into general use for poisoning by metals; known as British antilewisite or BAL.
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Chelation (pronounced Kee la shun) therapy started during World War I when poison gas (Lewisite) affected soldiers were treated with a chelating agent Dimercapol also known as British Anti Lewisite (BAL).
Caution Is Advised before Undergoing Chelation Therapy by Holly Dodd / Business community
By late 1918, 10 tons per day of lewisite were being produced in Cleveland, with the goal of having 3,000 tons for battlefield use by March 1, 1919.
Upton native's role was the best defense; WWI masks thwarted poison ... by Telegram & Gazette (Worcester, MA)
The exclusion criteria for experimental and epidemiologic studies were a) no original research (reviews, editorials, nonresearch letters); b) studies performed only on people with diabetes, including case reports; c) lack of outcomes related to diabetes or glucose metabolism; d) no data on arsenic exposure; e) experiments in nonmammalian cells, or noncellular experiments; f) animal studies administering a single dose of arsenic; and g) culture cell experiments using lewisite or oxophenylarsine.
Arsenic exposure and type 2 diabetes: a systematic review of the ... by Guallar, Eliseo / Environmental Health Perspectives
 
 
 
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