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Levodopa |
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levodopa /le·vo·do·pa/ (-do´pah) -dopa; the levorotatory isomer of dopa, used as an antiparkinsonian agent.
Levodopa (L-dopa) A substance used in the treatment of Parkinson's disease. Levodopa can cross the blood-brain barrier that protects the brain. Once in the brain, it is converted to dopamine and thus can replace the dopamine lost in Parkinson's disease. Mentioned in: Movement Disorders levodopa (lev´ōdō´p n brand names: Larodopa, Dopar; class drug: antiparkinson agent; action: levodopa is decarboxylated to dopamine, which can interact with dopamine receptors; uses: parkinsonism or parkinsonian symptoms. levodopa, L-DOPA the pharmaceutical name for dopa. levodopa Neuropharmacology The l- isomer of dopa, which is converted in vivo into dopamine, and used as a first-line anti-Parkinsonian agent Therapeutic range 0.2–0.3 µg/mL How to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit webmaster's page for free fun content. |
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| Analysis will span the de novo stage, early in the disease process before levodopa or other PD medications have commenced, through to end-stage disease, which is often 20 to 30 years later. Imaging can also reveal the effect of Parkinson's therapies such as levodopa, which replaces depleted dopamine, and deep-brain stimulation, in which doctors install in the brain a pacemakerlike device that sends electric pulses to target areas to prevent the signals that cause tremors and rigidity (SN: 3/12/05,p. In a randomized controlled trial, we investigated the effects of a single dose of levodopa on T-reflex amplitude in sexually aroused men and women. |
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