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leuprolide

   Also found in: Wikipedia 0.01 sec.
leuprolide /leu·pro·lide/ (loo-pro´līd) a synthetic analogue of gonadotropin-releasing hormone, used in the form of the acetate ester as an antiendometriotic agent, antineoplastic, and gonadotropin inhibitor.
leuprolide
Viadur® An analogue of gonadotropin-releasing hormone, which has been used to manage PMS, and block ovarian or testicular hormone production in Pts with hormonally active CA. See PMS.


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Dickey (1992) reported on a treatment resistant case of pedophilia that had failed to respond to both MPA and CPA and was successfully treated with leuprolide acetate.
The first study, conducted by McLeod on 255 patients, compared Abarelix with the combination of leuprolide and bicalutamide, the current hormonal therapy.
Finally, leuprolide was approved by FDA in January 2002 for the palliative treatment of advanced prostate cancer.
 
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