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leukotrienes

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Leukotrienes
A class of small molecules produced by cells in response to allergen exposure; they contribute to allergy and asthma symptoms.

leukotrienes
[lo̅o̅′kətrī′ēnz]
a class of biologically active compounds that occur naturally in leukocytes and produce allergic and inflammatory reactions similar to those of histamine. They are thought to play a role in the development of allergic and autoallergic diseases such as asthma, rheumatoid arthritis, inflammatory bowel disease, and psoriasis.

leukotrienes (lōō·kō·trī·ēnz),
n.pl regulators of inflammatory and allergic reactions. Biologically active leukotrienes are made up of 20-carbon carboxylic acids derived from arachidonic acid.


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The gene expression of enzymes COX-2, 5-LOX, FLAP and COX-1 were monitored and the products these enzymes generate, prostaglandins and leukotrienes, were quantified.
Leukotriene Modifiers Leukotrienes are derived from arachidonic acid and are preformed mediators located within mast cells.
Addition of the eicosatetraenoid products of 5-lipoxygenase (5-HETEs) showed stimulation of prostate cancer cell growth similar to that of arachidonic acid, whereas the leukotrienes were ineffective.
 
 
 
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