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Leukotrienes |
Also found in: Dictionary/thesaurus, Wikipedia, Hutchinson | 0.07 sec. |
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Leukotrienes A class of small molecules produced by cells in response to allergen exposure; they contribute to allergy and asthma symptoms. Mentioned in: Leukotriene Inhibitors leukotrienes (lōō·kō·trī·ēnz), n.pl regulators of inflammatory and allergic reactions. Biologically active leukotrienes are made up of 20-carbon carboxylic acids derived from arachidonic acid. |
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? Mentioned in | ? References in periodicals archive | ||
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| Among the inflammatory mediators released from mast cells, cysteinyl leukotrienes (cysLTs) have been shown to cause airway inflammation and airway smooth muscle contraction during RSV infection, accounting for the wheezing observed in bronchiolitis. This results from the inability of phagocyte oxidase to degrade inflammatory mediators such as leukotrienes, complement, and perhaps other components. The antibodies signal mast cells and basophils to release inflammatory chemicals such as histamine, prostaglandins and leukotrienes, which, in turn, trigger allergy-related symptoms like runny nose, scratchy eyes and sneezing. |
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Leukotrienes
