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Leukine

   Also found in: Wikipedia 0.03 sec.
Leukine®
Sargramostim Oncology A formulation of GM-CSF used for cell recovery in Pts with ↓ cell counts due to chemotherapy with Immunex. See GM-CSF.


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The product was withdrawn because of an upward trend in spontaneous reports of adverse reactions, including syncope (fainting), which are temporally correlated with a change in the formulation of liquid Leukine to include edetate disodium (EDTA).
The Federal Trade Commission proposed an order that would allay antitrust concerns by making Immunex sell its cancer-fighting drug Leukine to Schering AG.
At issue was whether the assay for making Leukine (sargramostim) was validated either by Abbot or Seattle-based Immunex, which licensed the product to Abbott.
 
 
 
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