chronic lymphocytic leukemia (redirected from Leukemia, lymphocytic, chronic)

leukemia /leu·ke·mia/ (loo-ke´me-ah) a progressive, malignant disease of the blood-forming organs, marked by distorted proliferation and development of leukocytes and their precursors in the blood and bone marrow.leuke´mic

---

acute leukemia  leukemia in which the involved cell line shows little or no differentiation, usually consisting of blast cells; it comprises two types, acute lymphocytic leukemia and acute myelogenous leukemia.

acute granulocytic leukemia  acute myelogenous l.

acute lymphoblastic leukemia  (ALL) one of the two major categories of acute leukemia, characterized by anemia, fatigue, weight loss, easy bruising, thrombocytopenia, granulocytopenia with bacterial infections, bone pain, lymphadenopathy, hepatosplenomegaly, and sometimes spread to the central nervous system. It is subclassified on the basis of the surface antigens expressed, e.g., B-cell type, T-cell type.

acute lymphocytic leukemia  acute lymphoblastic l.

acute megakaryoblastic leukemia , acute megakaryocytic leukemia a form of acute myelogenous leukemia in which megakaryocytes are predominant and platelets are increased in the blood.

acute monocytic leukemia  an uncommon form of acute myelogenous leukemia in which the predominating cells are monocytes.

acute myeloblastic leukemia 

1. a common type of acute myelogenous leukemia in which myeloblasts predominate; it is divided into two types on the basis of degree of cell differentiation.

2. acute myelogenous l.

acute myelocytic leukemia  acute myelogenous l.

acute myelogenous leukemia  (AML) one of the two major categories of acute leukemia, with symptoms including anemia, fatigue, weight loss, easy bruising, thrombocytopenia, and granulocytopenia.

acute myeloid leukemia 

1. acute myeloblastic l. (1).

2. acute myelogenous l.

acute myelomonocytic leukemia  a common type of acute myelogenous leukemia, with both malignant monocytes and monoblasts.

acute nonlymphocytic leukemia  acute myelogenous l.

acute promyelocytic leukemia  acute myelogenous leukemia in which more than half the cells are malignant promyelocytes.

acute undifferentiated leukemia  (AUL) acute myelogenous leukemia in which the predominating cell is so immature it cannot be classified.

adult T-cell leukemia/lymphoma  (ATL) an adult-onset, subacute or chronic malignancy of mature T lymphocytes, believed to be caused by human lymphotropic virus type I.

aleukemic leukemia  a form in which the total white blood cell count in the peripheral blood is not elevated; it may be lymphocytic, monocytic, or myelogenous.

basophilic leukemia  leukemia in which the basophilic leukocytes predominate.

chronic leukemia  leukemia in which the involved cell line is well differentiated, usually B lymphocytes, but immunologically incompetent.

chronic granulocytic leukemia  chronic leukemia of the myelogenous type, usually associated with a specific chromosomal abnormality and occurring in adulthood.

chronic lymphocytic leukemia  (CLL) chronic leukemia of the lymphoblastic type, characterized by lymphadenopathy, fatigue, renal involvement, and pulmonary leukemic infiltrates.

chronic myelocytic leukemia , chronic myelogenous leukemia, chronic myeloid leukemia chronic granulocytic l.

chronic myelomonocytic leukemia  a chronic, slowly progressing form characterized by malignant monocytes and myeloblasts, splenomegaly, and thrombocytopenia.

leukemia cu´tis  a cutaneous manifestation of leukemia resulting from infiltration of the skin by malignant leukocytes.

eosinophilic leukemia  a form in which eosinophils are the predominating cells.

granulocytic leukemia  myelogenous l.

hairy cell leukemia  chronic leukemia marked by splenomegaly and an abundance of large, mononuclear abnormal cells with numerous irregular cytoplasmic projections that give them a flagellated or hairy appearance in the bone marrow, spleen, liver, and peripheral blood.

histiocytic leukemia  acute monocytic l.

lymphatic leukemia , lymphoblastic leukemia, lymphocytic leukemia a form associated with hyperplasia and overactivity of the lymphoid tissue, with increased levels of circulating malignant lymphocytes or lymphoblasts.

lymphogenous leukemia , lymphoid leukemia lymphatic l.

lymphosarcoma cell leukemia  (B-cell type) acute lymphoblastic l.

mast cell leukemia  a rare form marked by overwhelming numbers of tissue mast cells in the peripheral blood.

megakaryoblastic leukemia  acute megakaryocytic l.

megakaryocytic leukemia 

1. acute megakaryocytic l.

2. hemorrhagic thrombocythemia.

micromyeloblastic leukemia  a form of myelogenous leukemia in which the immature nucleoli-containing cells are small and similar to lymphocytes.

monocytic leukemia  acute monocytic l.

myeloblastic leukemia 

1. myelogenous l.

2. acute myeloblastic l.

myelocytic leukemia , myelogenous leukemia, myeloid granulocytic leukemia a form arising from myeloid tissue in which the granular polymorphonuclear leukocytes and their precursors predominate. See also acute myelogenous l. and chronic granulocytic l.

myelomonocytic leukemia  acute myelomonocytic l.

plasma cell leukemia , plasmacytic leukemia a form in which the predominating cell in the peripheral blood is the plasma cell.

promyelocytic leukemia  acute promyelocytic l.

Rieder cell leukemia  a form of acute myelogenous leukemia in which the blood contains asynchronously developed cells with immature cytoplasm and a lobulated, relatively more mature nucleus.

stem cell leukemia  acute undifferentiated l.

---

chronic lymphocytic leukemia

n. Abbr. CLL

Lymphocytic leukemia occurring mainly in older adults, characterized by slow onset and gradual progression of symptoms.

---

Chronic lymphocytic leukemia

A cancer of the blood cells characterized by large numbers of cancerous, mature white blood cells and enlarged lymph nodes.

Mentioned in: Beta 2 -Microglobulin Test

---

chronic lymphocytic leukemia (CLL)

Etymology: Gk, chronos + L, lympha, water; Gk, kytos, cell, leukos, white, haima, blood

a neoplasm of blood-forming tissues, characterized by a proliferation of small, long-lived lymphocytes, chiefly B cells, in bone marrow, blood, liver, and lymphoid organs. CLL is the rarest type of leukemia and the only leukemia to which there is a possible genetic predisposition. CLL is rare in persons less than 50 years of age, increases in frequency with age, and is more common in men than in women. The disease has an insidious onset and progresses to cause malaise, ready fatigability, anorexia, weight loss, nocturnal sweating, lymphadenopathy, and hepatosplenomegaly. Most patients can continue normal activities for years; 25% die of unrelated diseases. No treatment is curative, but remissions may be induced by chemotherapy or irradiation. See also acute lymphocytic leukemia.

---

chronic lymphocytic leukemia

Chronic lymphoblastic lymphoma Hematology A slowly progressive form of leukemia more often seen in older adults, which is characterized by ↑ mature lymphocytes Clinical Variable Sx; CLL may be diagnosed fortuitously during a routine CBC for an unrelated illness, before clinical disease Cf Chronic myelocytic leukemia.

Chronic lymphocytic leukemia–stages

  0 Lymphocytosis in blood, without other Sx of leukemia

  I Lymphocytosis; lymphadenopathy

 II Lymphocytosis; lymphadenopathy; hepatosplenomegaly

III Lymphocytosis; lymphadenopathy; hepatosplenomegaly, anemia

IV Lymphocytosis, lymphadenopathy; hepatosplenomegaly, thrombocytopenia ± anemia