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Letterer-Siwe disease

   Also found in: Dictionary/thesaurus, Acronyms, Encyclopedia, Wikipedia, Hutchinson 0.06 sec.
Let·ter·er-Si·we disease (ltr-r-sw, -sv)
n.
See nonlipid histiocytosis.
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1) At that time, histiocytosis X was subdivided into three types: (1) eosinophilic granuloma, an isolated osteolytic lesion: (2) Hand-Schuller-Christian disease, a multifocal version of eosinophilic granuloma that is often accompanied by systemic manifestations; and (3) Letterer-Siwe disease, a systemic, rapidly progressive form of histiocytosis X.
Langerhans' cell histiocytosis: current trends and the role of the ... by Rice, Dale H. / Ear, Nose and Throat Journal
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