PKC plans to evaluate the effectiveness of this strategy in an upcoming clinical trial in patients diagnosed with leptomeningeal carcinomatosis
and who have also had HER2 positive breast cancer.
Valerie has been diagnosed with leptomeningeal carcinomatosis
, which is very rare and usually a secondary or metastatic cancer.
Follow-up tests revealed Harper had leptomeningeal carcinomatosis, a rare type of cancer that occurs in the meninges, thin membranes, that surrounds the brain and spinal cord.
Leptomeningeal carcinomatosis is a condition where cancerous cells are found in the arachnoid mater and pia mater, the second innermost and innermost layers of the meninges.
The aim of this study was to compare the sensitivity of gadolinium-enhanced T1-weighted MRI and gadolinium-enhanced FLAIR MR imaging in detecting leptomeningeal carcinomatosis
Beta-glucuronidase -- A normal enzyme occurring abnormally in CSF in leptomeningeal carcinomatosis
Differential diagnosis after imaging studies were completed included the possibility of infectious meningitis, leptomeningeal carcinomatosis
, or meningioma.
In cases of breast cancer, the diagnoses of parenchymal brain metastases and leptomeningeal carcinomatosis
are often delayed (1).
Marc Chamberlain, MD -- Professor of Neurology, University of Washington, a world renowned neuro-oncologist, well known for his work on leptomeningeal carcinomatosis
This is one of a handful of reported cases of a clinically undiagnosed gallbladder carcinoma presenting as leptomeningeal carcinomatosis
News of television icon Valerie Harper's diagnosis has renewed interest in the devastating diagnosis of Leptomeningeal Carcinomatosis
Dural metastatic disease was approximately equal in frequency to that for another rare pattern of central nervous system cancer spread, leptomeningeal carcinomatosis