LEP


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LEP

A gene on chromosome 7q31.3 that encodes leptin, a protein secreted by white adipocytes, which plays a key role in regulating body weight. By binding to its cognate receptor, leptin is part of a signalling pathway which inhibits food intake and regulates energy expenditure to maintain fat homeostasis. Leptin plays a role in the endocrine system, and is involved in regulating immune and inflammatory responses, haematopoiesis, angiogenesis, reproduction, glucose homeostasis, bone formation, and wound healing.

Molecular pathology
Mutations of LEP and/or its regulatory regions are linked to obesity, morbid obesity with hypogonadism, and type-2 diabetes.

LEP

low egg passage, with reference to virus attenuation usually for vaccine production.
References in periodicals archive ?
Separately, there is going to have to be a new settlement on how local government and the mayor and the LEP work together.
Stopping the promotion of Mr Land - a LEP board member - comes after Bob Paton was put in place as LEP chief executive in April.
The 39 LEPs in England, all led by business, are working with local partners on devolution deals aimed at accelerating economic growth and creating new jobs.
The scope of this LEP includes refurbishment of both nuclear and non-nuclear components to address aging, ensure extended service life and improve safety, reliability and security of the bomb.
If so, at least some of the territory served by Coventry and Warwickshire LEP will also be included in the combined authority.
In terms of LEP performance, it was found that students who learnt science and mathematics in Tamil achieve the highest score of 11.
John Cuthbert, chairman of the Northern Business Forum, and the main signatory on the controversial letter, said Teesside's early bid for LEP status was "understandable" but that having looked at other LEP bids and there was now a need to bring in a "wider geography".
More than 20 percent of students in Clark County schools, 62,734 were classified as LEP in 2008-09, at a cost to the county of $615.
In the year 2000, the number of LEP (Limited English Proficient) students nationwide was estimated at 2.
Cambridge Display Technology (CDT), the owner and licensor of the fundamental intellectual property in light emitting polymer (LEP) OLED technology, and DuPont Displays, a business unit of DuPont, have announced an agreement to provide CDT's full color ink jet printing manufacturing technology to DuPont for use in its LEP OLED manufacturing.
The competing pedagogical model for teaching LEP students is known as English as a Second Language (ESL) instruction, ESL is essentially a program of English immersion with special instruction geared toward the acquisition of English-language skills.