Lennox-Gastaut syndrome

(redirected from Lennox syndrome)

Len·nox-Gas·taut syn·drome

(len'ŏks gahs-tō),
a generalized myoclonic astatic epilepsy in children, with mental retardation, resulting from various cerebral afflictions such as perinatal hypoxia, cerebral hemorrhage, encephalitides, and maldevelopment or metabolic disorders of the brain; characterized by multiple seizure types (generalized tonic, atonic, myoclonic, tonic-clonic, and atypical absence) and background slowing and slow spike and wave pattern on EEG.
Synonym(s): Lennox syndrome

Lennox-Gastaut syndrome

[len′oks-gästō′]
Etymology: William G. Lennox, American neurologist, 1884-1960; Henri Gastaut, French biologist, b. 1914
a condition in which a variety of generalized seizures, such as tonic, atonic, absence, tonic-clonic, akinetic, and myoclonic, begin to appear in the first 5 years of life. Seizures are often intractable and may require multiple antiepileptic medications. Mental retardation is often present. Among suggested causes are inherited metabolic abnormalities and perinatal or postnatal disorders. Also called Gastaut's disease.

Lennox-Gastaut syndrome

Lennox syndrome Neurology A severe encephalopathic form of epilepsy that constitutes 5% of all childhood epilepsies Clinical Early onset of multiple types–eg, absence, atonic, and others of seizures, slow spike-wave EEG pattern, cerebral atrophy, and often progressive mental retardation; seizures are poorly controlled even with multiple anticonvulsants Prognosis For cognitive development, poor; felbamate may ↓ Sx. See Felbamate.

Len·nox-Gas·taut syn·drome

, Lennox syndrome (len'ŏks gahs-tō' sin'drōm)
A generalized myoclonic astatic epilepsy in children, with mental retardation, resulting from various cerebral afflictions such as perinatal hypoxia, cerebral hemorrhage, encephalitides, maldevelopment or metabolic disorders of the brain; characterized by multiple seizure types (generalized tonic, atonic, myoclonic, tonic-clonic, and atypical absence) and background slowing and slow spike and wave pattern on electroencephalogram; patients are usually mentally retarded or developmentally delayed.

Gastaut,

Henri, French biologist, 1915–.
Gastaut syndrome - juvenile hemiplegic epilepsy with ipsilateral signs.
Lennox-Gastaut syndrome - see under Lennox

Lennox,

William G., U.S. neurologist, 1884-1960.
Lennox-Gastaut syndrome - a generalized myoclonic astatic epilepsy in children, with mental retardation. Synonym(s): Lennox syndrome
Lennox syndrome - Synonym(s): Lennox-Gastaut syndrome