Leishmania tropica


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Leishmania

 [lēsh-ma´ne-ah]
a genus of protozoa comprising parasites of worldwide distribution, several species of which are pathogenic for humans. All species are morphologically indistinguishable, and therefore the organisms have usually been assigned to species and subspecies according to their geographic origin, the clinical syndrome they produce, and their ecologic characteristics. They have also been separated based on their tendency to cause visceral, cutaneous, or mucocutaneous leishmaniasis. In some classifications, Leishmania is grouped in four complexes comprising species and subspecies: L. donovani, L. tropica, L. mexicana, and L. viannia.
Life cycle of Leishmania. From Mahon and Manuselis, 2000.
Leishmania brazilien´sis Leishmania viannia.
Leishmania donova´ni donova´ni a subspecies of the L. donovani complex causing the classic form of visceral leishmaniasis in India. It is transmitted by the sandfly Phlebotomus argentipes, with humans being the only major reservoir hosts. Called also L. donovani.
Leishmania ma´jor a species of the L. tropica complex, transmitted by Phlebotomus papatasi, causing the rural form of Old World cutaneous leishmaniasis. Called also L. tropica major.
Leishmania mexica´na a complex comprising the species and subspecies causing the New World form of cutaneous leishmaniasis in humans: L. m. mexicana, L. m. amazonensis, and L. pifanoi.
Leishmania tro´pica
1. a complex comprising the species causing the Old World form of cutaneous leishmaniasis: L. tropica, L. major, and L. aethiopica.
2. a species of the L. tropica complex causing the urban form of Old World cutaneous leishmaniasis. It is found in Iran, Iraq, and India, transmitted by Phlebotomus sergenti; and in southern France, Italy and certain Mediterranean islands, transmitted by P. papatasi. Human to human transmission may also occur.
Leishmania vian´nia a taxonomic complex comprising the subspecies that cause mucocutaneous leishmaniasis in its various forms; all of the subspecies develop in the midgut, foregut, and hindgut of their sandfly vectors. Formerly called L. braziliensis.

Leish·man·i·a tro·pi·ca

species that is the causal agent of anthroponotic cutaneous leishmaniasis; formerly endemic throughout the Mediterranean basin, the Middle East, parts of the Caucasus region and elsewhere in Asia, and also reported from western Africa; it is transmitted by Phlebotomus papatasi, P. sergenti, and related species of sandflies; small rodents such as various ground squirrels serve as reservoir hosts.

Leishmania tropica

The causative agent of Oriental sore (cutaneous leishmaniasis).
See also: Leishmania

Leishmania

a genus of protozoan parasites transmitted by sandflies, which also act as intermediate hosts.

Leishmania adleri
found in lizards and other mammals.
Leishmania aethiopica
reservoir hosts are hyraxes.
Leishmania brasiliensis brasiliensis
reservoir hosts are forest rodents. Causes mucocutaneous leishmaniasis in humans.
Leishmania brasiliensis guyanensis
dogs are infected; in humans the disease is the cutaneous form in most cases.
Leishmania brasiliensis panamensis
reservoirs are sloths, kinkajous and many other forest animals.
Leishmania chagasi
causes visceral leishmaniasis in humans and dogs.
Leishmania donovani
causes visceral leishmaniasis in humans and in carnivores.
Leishmania enriettii
causes cutaneous leishmaniasis in guinea pigs.
Leishmania infantum
causes visceral leishmaniasis in dogs and other carnivores. In humans it is children who are most commonly affected.
Leishmania major
dogs and bush mammals are reservoir hosts. In humans this is the cause of oriental sore, the important cutaneous form of the disease.
Leishmania mexicana amazonensis
causes cutaneous leishmaniasis in humans. Rodents and bush animals are reservoir hosts.
Leishmania mexicana mexicana
reservoir hosts are rodents; causes cutaneous leishmaniasis in humans.
Leishmania mexicana pifanoi
causes chronic cutaneous leishmaniasis in humans.
Leishmania peruviana
causes cutaneous leishmaniasis in humans; probably infests dogs.
Leishmania tropica
causes cutaneous leishmaniasis in humans and dogs.
References in periodicals archive ?
Involvement of thiol metabolism in resistance to glucantime in Leishmania tropica.
The 9 lanes contain a molecular-weight "ladder" (lane 1), the products from reference strains of Leishmania tropica (lane 2), and Leishmania major (lane 3), a negative control (lane 5), and test samples identified as L tropica (lane 4) and L major (lanes 6-9).
Phlebotomus sergenti, a vector of Leishmania tropica in Saudi Arabia.
New natural sesquiterpenes as modulators of daunomycin resistance in a multidrug-resistant Leishmania tropica line.
29) against Leishmania tropica promastigotes while N3 exhibited the most potent activity (IC50= 68.
Leishmania tropica in northern Israel: a clinical overview of an emerging focus.
Leishmania tropica a causative agent of cutaneous leishmaniasis (CL) is transmitted from person-to-person through Phlebotomus (Paraphlebotomus) sergenti in urban settings (5).
The cutaneous form of the disease is caused mainly in Pakistan by Leishmania tropica and L.
Following the Persian Gulf War, a viscerotropic form of Leishmania tropica infection was described, and acquired immunodeficiency syndrome-associated disease is increasingly important.
In at least five of the cases, the species of the the infecting parasite was Leishmania tropica (previously known as L.
Anti-leishmanial activity was performed against Leishmania tropica promastigote stage parasite while insecticidal activity was assessed through brine shrimps lethality assay.