leiomyoma

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Related to Leiomyomas: leiomyomata

leiomyoma

 [li″o-mi-o´mah]
a benign tumor derived from smooth muscle, most often of the uterus (leiomyoma uteri).
bizarre leiomyoma epithelioid leiomyoma.
leiomyoma cu´tis one arising from cutaneous or subcutaneous smooth muscle fibers, found singly or multiply, usually as lesions arising from arrectores pilorum muscles; it may also occur as a solitary genital lesion or a solitary angioleiomyoma arising from the muscle of veins.
epithelioid leiomyoma one in which the cells are polygonal rather than spindle shaped, usually found in the stomach. Called also bizarre leiomyoma and leiomyofibroma.
leiomyoma u´teri (uterine leiomyoma) leiomyoma of the uterus; called also uterine myoma and, colloquially, fibroids. It is the most common of all tumors found in women. It may occur in any part of the uterus, although it is most frequently in the body of the organ.

Leiomyomas usually occur during the third and fourth decades, and are often multiple, although a single tumor may occur. They are usually small but may grow quite large and occupy most of the uterine wall; after menopause, growth usually ceases. Symptoms vary according to the location and size of the tumors. As they grow they may cause pressure on neighboring organs, painful menstruation, profuse and irregular menstrual bleeding, vaginal discharge, or frequent urination, as well as enlargement of the uterus.

In pregnancy, the tumors may interfere with natural enlargement of the uterus with the growing fetus. They may also cause spontaneous abortion and death of the fetus.

Small leiomyomas are usually left undisturbed and are checked at frequent intervals. Larger tumors may be removed surgically, sometimes accompanied by a hysterectomy, or medication may be prescribed to induce a temporary menopause.
Leiomyoma of the uterus. The tumors may be subserosal, intramural, or submucosal. Subserosal and submucosal tumors may be pedunculated and may protrude from the uterine surface or into the uterine cavity, respectively. The stalk of pedunculated tumors may also become twisted. From Damjanov, 2000.

lei·o·my·o·ma

(lī'ō-mī-ō'mă),
A benign neoplasm derived from smooth (nonstriated) muscle.
[leio- + G. mys, muscle, + -oma, tumor]

leiomyoma

/leio·myo·ma/ (-mi-o´mah) a benign tumor derived from smooth muscle, most often of the uterus.
leiomyoma cu´tis  one or more smooth, firm, painful, often waxy nodules arising from cutaneous or subcutaneous smooth muscle fibers.
epithelioid leiomyoma  leiomyoma, usually of the stomach, in which the cells are polygonal rather than spindle shaped.

leiomyoma

(lī′ō-mī-ō′mə)
n. pl. leiomyo·mas or leiomyo·mata (-mə-tə)
A benign tumor derived from smooth muscle, occurring most often in the uterus.

lei′o·my·o′ma·tous (-ō′mə-təs, -ŏm′ə-) adj.

leiomyoma

[lī′ōmī·ō′mə] pl. leiomyomas, leiomyomata
a benign smooth-muscle tumor occurring most commonly in the uterus, stomach, esophagus, or small intestine. Surgical resection is usually indicated.
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Leiomyomas

leiomyoma

Fibroma, plural, leiomyomata or, incorrect, but increasingly popular, leiomyomas A benign, well-circumscribed smooth muscle tumor most common in the uterus and stomach. See Fibroid, Fibroma, Intestinal leiomyoma.

lei·o·my·o·ma

(lī'ō-mī-ō'mă)
A benign neoplasm derived from smooth (nonstriated) muscle.
[leio- + G. mys, muscle, + -oma, tumor]

leiomyoma

A benign tumour of smooth muscle found most commonly in the womb (uterus). Leiomyomas often contain much fibrous tissue. Also known as FIBROID, fibromyoma or leiomyofibroma.

Leiomyoma

A benign tumor composed of muscle tissue. Leiomyomas in the uterus are sometimes called fibroids.
Mentioned in: Hysterosonography

leiomyoma

vascular smooth-muscle-derived benign neoplasm; firm, smooth subcutaneous nodule with associated local stabbing pain; treated by local excision

lei·o·my·o·ma

(lī'ō-mī-ō'mă)
A benign neoplasm derived from smooth (nonstriated) muscle.
[leio- + G. mys, muscle, + -oma, tumor]

leiomyoma (lī´ōmīō´mə),

n a benign tumor derived from smooth muscle.

leiomyoma

a benign tumor derived from smooth muscle, most often of the uterus (leiomyoma uteri) but can occur in urinary bladder, upper intestinal tract and esophagus.

leiomyoma uteri
leiomyoma of the uterus; called also colloquially, fibroids.

Patient discussion about leiomyoma

Q. uterine fibroids. Whats the best way to deal with them? My doctor says hysterectomy? What about my hormones?

A. Yes, drugs that suppress the levels of the female sex hormones (estrogen) are successful for treating uterine fibroids. However, the relief is only temporary and the fibroids recur once the treatment is stopped. In addition, these treatments cause side effects similar to menopause.

Surgery is the definitive treatment, especially for complications such as bleeding or pain, and when there's a suspicion for malignancy.

You may read more here: http://www.nlm.nih.gov/medlineplus/ency/article/000914.htm

More discussions about leiomyoma
References in periodicals archive ?
No statistically significant differences were observed in the dimension of leiomyomas in relation to treatment with estroprogestins (5.
3) CECT features of uterine leiomyomas are soft-tissue density, exhibit coarse peripheral or central calcification.
CYP1A1 and CYP1B1 genetic polymorphisms and uterine leiomyoma risk in Chinese women.
Final pathology results of resected specimens again identified fragments of benign leiomyoma, confirming the diagnosis of DPL.
According to the AAGL's practice guidelines on the diagnosis and management of submucous leiomyomas, it "seems clear from high-quality studies that pregnancy rates are higher after myomectomy than no or 'placebo' procedures" (J.
Histology confirmed a benign leiomyoma macroscopically measuring 5 x 3.
Esophageal/gastric leiomyoma in the laboratory Beagle.
1) Leiomyoma is the most common benign mesothelial tumor, which is rarely encountered in the genitourinary tract.
Another recognized morphologic variant of leiomyoma is intravenous (IV) leiomyomatosis (2); the presence of leiomyomas within vascular spaces outside of a leiomyoma, which are often grossly visible.
Progesterone receptor modulator CDB-2914 down regulates proliferative cell nuclear antigen and Bcl-2 protein expression and up-regulates caspase-3 and poly(adenosine 5'-diphosphateribose) polymerase expression in cultured human uterine leiomyoma cells," Journal of Clinical Endocrinology& Metabolism 90(2): 953-961.
NASDAQ: BSMD) ("BioSphere" or the "Company") - the pioneer in the use of bioengineered microspheres to treat uterine fibroids, hypervascularized tumors and vascular malformations by a minimally invasive, image-guided medical procedure called embolotherapy - reports the publication of a study in the October 2009 issue of the Journal of Vascular Interventional Radiology in which the authors conclude that uterine artery embolization (UAE) compares favorably to laparoscopic occlusion of uterine arteries in the treatment of uterine leiomyomas (fibroids) in cases where hysterectomy or myomectomy are not options.
HLRCC is a relatively rare autosomal dominant condition which causes cutaneous and uterine leiomyomas and early-onset RCC, typically papillary carcinoma type II.