leiomyoma

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leiomyoma

 [li″o-mi-o´mah]
a benign tumor derived from smooth muscle, most often of the uterus (leiomyoma uteri).
bizarre leiomyoma epithelioid leiomyoma.
leiomyoma cu´tis one arising from cutaneous or subcutaneous smooth muscle fibers, found singly or multiply, usually as lesions arising from arrectores pilorum muscles; it may also occur as a solitary genital lesion or a solitary angioleiomyoma arising from the muscle of veins.
epithelioid leiomyoma one in which the cells are polygonal rather than spindle shaped, usually found in the stomach. Called also bizarre leiomyoma and leiomyofibroma.
leiomyoma u´teri (uterine leiomyoma) leiomyoma of the uterus; called also uterine myoma and, colloquially, fibroids. It is the most common of all tumors found in women. It may occur in any part of the uterus, although it is most frequently in the body of the organ.

Leiomyomas usually occur during the third and fourth decades, and are often multiple, although a single tumor may occur. They are usually small but may grow quite large and occupy most of the uterine wall; after menopause, growth usually ceases. Symptoms vary according to the location and size of the tumors. As they grow they may cause pressure on neighboring organs, painful menstruation, profuse and irregular menstrual bleeding, vaginal discharge, or frequent urination, as well as enlargement of the uterus.

In pregnancy, the tumors may interfere with natural enlargement of the uterus with the growing fetus. They may also cause spontaneous abortion and death of the fetus.

Small leiomyomas are usually left undisturbed and are checked at frequent intervals. Larger tumors may be removed surgically, sometimes accompanied by a hysterectomy, or medication may be prescribed to induce a temporary menopause.
Leiomyoma of the uterus. The tumors may be subserosal, intramural, or submucosal. Subserosal and submucosal tumors may be pedunculated and may protrude from the uterine surface or into the uterine cavity, respectively. The stalk of pedunculated tumors may also become twisted. From Damjanov, 2000.

lei·o·my·o·ma

(lī'ō-mī-ō'mă),
A benign neoplasm derived from smooth (nonstriated) muscle.
[leio- + G. mys, muscle, + -oma, tumor]

leiomyoma

/leio·myo·ma/ (-mi-o´mah) a benign tumor derived from smooth muscle, most often of the uterus.
leiomyoma cu´tis  one or more smooth, firm, painful, often waxy nodules arising from cutaneous or subcutaneous smooth muscle fibers.
epithelioid leiomyoma  leiomyoma, usually of the stomach, in which the cells are polygonal rather than spindle shaped.

leiomyoma

(lī′ō-mī-ō′mə)
n. pl. leiomyo·mas or leiomyo·mata (-mə-tə)
A benign tumor derived from smooth muscle, occurring most often in the uterus.

lei′o·my·o′ma·tous (-ō′mə-təs, -ŏm′ə-) adj.

leiomyoma

[lī′ōmī·ō′mə] pl. leiomyomas, leiomyomata
a benign smooth-muscle tumor occurring most commonly in the uterus, stomach, esophagus, or small intestine. Surgical resection is usually indicated.
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Leiomyomas

leiomyoma

Fibroma, plural, leiomyomata or, incorrect, but increasingly popular, leiomyomas A benign, well-circumscribed smooth muscle tumor most common in the uterus and stomach. See Fibroid, Fibroma, Intestinal leiomyoma.

lei·o·my·o·ma

(lī'ō-mī-ō'mă)
A benign neoplasm derived from smooth (nonstriated) muscle.
[leio- + G. mys, muscle, + -oma, tumor]

leiomyoma

A benign tumour of smooth muscle found most commonly in the womb (uterus). Leiomyomas often contain much fibrous tissue. Also known as FIBROID, fibromyoma or leiomyofibroma.

Leiomyoma

A benign tumor composed of muscle tissue. Leiomyomas in the uterus are sometimes called fibroids.
Mentioned in: Hysterosonography

leiomyoma

vascular smooth-muscle-derived benign neoplasm; firm, smooth subcutaneous nodule with associated local stabbing pain; treated by local excision

lei·o·my·o·ma

(lī'ō-mī-ō'mă)
A benign neoplasm derived from smooth (nonstriated) muscle.
[leio- + G. mys, muscle, + -oma, tumor]

leiomyoma (lī´ōmīō´mə),

n a benign tumor derived from smooth muscle.

leiomyoma

a benign tumor derived from smooth muscle, most often of the uterus (leiomyoma uteri) but can occur in urinary bladder, upper intestinal tract and esophagus.

leiomyoma uteri
leiomyoma of the uterus; called also colloquially, fibroids.

Patient discussion about leiomyoma

Q. uterine fibroids. Whats the best way to deal with them? My doctor says hysterectomy? What about my hormones?

A. Yes, drugs that suppress the levels of the female sex hormones (estrogen) are successful for treating uterine fibroids. However, the relief is only temporary and the fibroids recur once the treatment is stopped. In addition, these treatments cause side effects similar to menopause.

Surgery is the definitive treatment, especially for complications such as bleeding or pain, and when there's a suspicion for malignancy.

You may read more here: http://www.nlm.nih.gov/medlineplus/ency/article/000914.htm

More discussions about leiomyoma
References in periodicals archive ?
We report a case of leiomyoma of bladder after taking written and informed consent from a 38 years old female, after obtaining the permission of the institutional review board (IRB).
Leiomyoma of the anterior vaginal wall in a suburethral location causing stress incontinence: report of a case.
Mutations in or overexpression of p53 have been determined to be significant in LMSs (25%-47%) but are rarely observed in benign leiomyomas (1-3, 5).
Leiomyoma is a non-malignant tumor of smooth muscle origin, which is an important member of mesenchymal neoplasms involving the gastrointestinal tract and uterus.
Schwannomas are S100 positive, GIST are CD 117 and DOG1 positive, leiomyoma and leiomyasarcoma shows positivity for Smooth muscle actin and desmin.
Oral leiomyomas are rare benign tumors of the oral cavity that are hypothesized to originate from excretory ducts of salivary glands and vascular smooth muscles (5).
Cadmium and proliferation in human uterine leiomyoma cells: evidence of a role for EGFR/MAPK pathways but not classical estrogen receptor pathways.
Of note, mitotic index will be higher near necrotic areas or in ulcerated areas of leiomyomas, therefore one should stay away from counting mitoses in these areas.
Role of MR imaging of uterine leiomyomas before and after embolization.
Although the pathogenesis remains unclear; one theory suggested that leiomyomas originate from the vessel wall12 whereas according to another theory, the uterine fibroids invaded into the uterine vein13, which is similar to our case.
Fumarate hydratase mutations and predisposition to cutaneous leiomyomas, uterine leiomyomas and renal cancer.