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lecithin-cholesterol acyltransferase

   Also found in: Acronyms, Wikipedia 0.03 sec.
lecithin–cholesterol acyltransferase /lec·i·thin–cho·les·ter·ol ac·yl·trans·fer·ase/ (LCAT) (kah-les´ter-ol a″sil-trans´fer-ās) an enzyme that catalyzes the formation of cholesteryl esters in high-density lipoproteins; deficiency of enzyme activity, an inherited disorder, results in accumulation of cholesterol and phosphatidylcholine in plasma and tissues, which causes corneal opacities, anemia, and often proteinuria.


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Serum total cholesterol and high-density lipoprotein cholesterol concentrations and lecithin-cholesterol acyltransferase (LCAT) activity were measured before randomization and at treatment end-point.
 
 
 
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