Laron dwarfism

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Laron dwarfism

[lä·rôN′]

Etymology: Zvi Laron, Israeli endocrinologist, b. 1927

an autosomal-recessive syndrome of skeletal growth retardation resulting from impaired ability to synthesize insulin-like growth factor I, usually because of growth hormone receptor defects. Also called Laron's syndrome.

Laron dwarfism

Genetics An AR condition characterized by target resistance to the action of hGH, due to a defect in the hGH receptor Clinical Consanguinity, severe growth retardation Lab ↑ IGF-I

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growth hormone insensitivity syndrome
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