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lapatinib |
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lapatinib, a miscellaneous antineoplastic. indication This drug is used to treat advanced breast cancer in patients with tumors that overexpress HER2 protein and who have received previous chemotheraphy. contraindications Pregnancy, breastfeeding, torsade de points, and known hypersensitivity to this drug prohibit its use. adverse effects Adverse effects of this drug include fatigue, insomnia, palpitations, anorexia, diarrhea, dyspepsia, mouth ulcerations, nausea, vomiting, xerosis, rash, palmar-plantar erythrodysesthesia, and dyspnea. Life-threatening side effects include heart failure, QT prolongation, anemia, neutropenia, and thrombocytopenia. How to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit webmaster's page for free fun content. |
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GSKs lapatinib and BMYs dasatinib are the early stars GlaxoSmithKlines lapatinib should represent a new standard of care for patients for HER2+ metastatic breast cancer patients that have progressed after Herceptin. The treatment of highly prevalent cancers such as breast, NSCLC and colorectal with a new first-line therapy for breast cancer, lapatinib (GSK), a third-generation oral platinum based therapy, Telcyta (Telik) and an interesting angiogenic kinase inhibitor, vatalanib for the treatment of advanced colorectal cancer from Novartis and Schering AG. |
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