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Langerhans' cells

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Langerhans' cells
[lung′ərhuns, lang′ərhans]
Etymology: Paul Langerhans, German pathologist, 1847-1888
a stellate dendritic cell found mostly in the stratum spinosum of the epidermis. It is believed to have an immune function, with surface markers characteristic of macrophages and monocytes.


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Introduction Pulmonary Langerhans'-cell histiocytosis LCH) forms part of a spectrum of diseases characterized by monoclonal proliferation and infiltration of organs by Langerhans' cells (1).
After analysing biopsy samples from 10 uncircumcised and 10 circumcised men, researchers found that the inner foreskin has a significantly higher density of Langerhans' cells than other areas of the foreskin.
7) Because Langerhans' cells are the only monoclonal cells in LCH, Egeler et al speculated that LCH is a type of neoplastic phenomenon.
 
 
 
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