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Lactic acidosis

   Also found in: Dictionary/thesaurus, Wikipedia, Hutchinson 0.04 sec.
Lactic acidosis
A serious condition caused by the build up of lactic acid in the blood, causing it to become excessively acidic. Lactic acid is a by-product of glucose metabolism.
Mentioned in: Diabetic Ketoacidosis
lactic acidosis Metabolism Metabolic acidosis due to ↑ lactic acid resulting from tissue hypoxia or ↓ conversion of lactate to pyruvate Etiology Exercise, endogenous or exogenous metabolic defects Lab ↓ Bicarbonate, ↓ pH, ↑ anion gap, ↑ PO4 Treatment Dichloro-acetate treatment of Pts with severe LA results in statistically significant but clinically unimportant changes in the pH and arterial blood lactate and does not alter the hemodyanimcs or survival


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