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lactam
(redirected from Lactams)

    Also found in: Dictionary/thesaurus, Wikipedia 0.07 sec.
lactam /lac·tam/ (lak´tam) a cyclic amide formed from aminocarboxylic acids by elimination of water; lactams are isomeric with lactims, which are enol forms of lactams.
ß-lactam  see under antibiotic.
lac·tam (lktm)
n.
An amide formed from amino carboxylic acids containing a keto group in a ring configuration, as seen in purines, pyrimidines, and antibiotics. It is tautomeric to lactim.
lactam
a cyclic amide formed from aminocarboxylic acids by elimination of water; lactams are isomeric with lactims, which are enol forms of lactams.
ß-lactam antibiotics
includes the penicillins, cephalosporins, carbapenems and penems. See also ß-lactam ring (below).
ß-lactam ring
an integral part of the formula of ß-lactam antibiotics. Disruption of the ring by ß-lactamase produced by some bacteria, e.g. Escherichia coli, Bacillus anthracis, destroys the antimicrobial activity of the compound.
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Polyamides, better known as nylons, are made from the polymerization of lactams or the condensation of diamines with dicarboxylic acids.
Identification of polymers by IR spectroscopy by O'Keefe, Jerome F. / Rubber World
Among the metabolites of Stachybotrys are various compounds with obscure biologic activities: the simple trichothecenes trichodermol and trichodermin, which are precursors to the satratoxins; the diterpenoid dollabellanes and atranones; and a very large number of spirocyclic drimanes including Stachybotrys lactones and lactams (Hinkley et al.
Synergistic interaction in simultaneous exposure to Streptomyces ... by Hirvonen, Maija-Riitta / Environmental Health Perspectives
Individually, those organisms that have a natural resistance to certain beta lactams and beta-lactamase inhibitors--for example, some Enterobacteriaceae, Pseudomonas species, and Acinetobacter species--were not common in our study.
Bacteriologic findings in patients with chronic sinusitis by de Pepe, Marta G.D. / Ear, Nose and Throat Journal
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