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lactam
(redirected from Lactams)

   Also found in: Dictionary/thesaurus, Encyclopedia, Wikipedia 0.01 sec.
lactam /lac·tam/ (lak´tam) a cyclic amide formed from aminocarboxylic acids by elimination of water; lactams are isomeric with lactims, which are enol forms of lactams.
β-lactam  see under antibiotic.

lac·tam (lktm)
n.
An amide formed from amino carboxylic acids containing a keto group in a ring configuration, as seen in purines, pyrimidines, and antibiotics. It is tautomeric to lactim.

lactam
[lak′təm]
a cyclic amide created by the elimination of a molecule of water from aminocarboxylic acid. Lactim is the isomeric form of lactam.

lactam
a cyclic amide formed from aminocarboxylic acids by elimination of water; lactams are isomeric with lactims, which are enol forms of lactams.

β-lactam antibiotics
includes the penicillins, cephalosporins, carbapenems and penems. See also β-lactam ring (below).
β-lactam ring
an integral part of the formula of β-lactam antibiotics. Disruption of the ring by β-lactamase produced by some bacteria, e.g. Escherichia coli, Bacillus anthracis, destroys the antimicrobial activity of the compound.


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Some specific areas discussed include polyester materials with low specific superficial electric resistance, the effect of organic and inorganic additives on the synthesis of lutetium silicates, similarity of zeolite micropore structures, new complex compounds of cobalt with cyanuric acid, frontal copolymerization of lactams, and oscillatory and spin regimes at frontal solidification of epoxy combinations in the flow.
Steroidal-4-en-3-ones such as 4-cholesten-3-one were treated with ozone to obtain a keto acid, 3,5-seco-4-norcholestan-5-on-3-oic acid (I), subsequently treated with amines to obtain enamine lactams which were discovered to react with Grignard reagents at elevated temperatures to yield novel unsaturated 3-alkyl derivativatives.
The focus then shifts to a systematic presentation of the various substrates classes, namely carboxylic esters, amides and peptides, lactams and lactones, esters of inorganic acids, alkene and arene epoxides, and some miscellaneous hydrolyzable moieties.
 
 
 
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