antileukotriene (redirected from LTD4 receptor antagonists)

antileukotriene

Any of a class of agents that either interfere with leukotriene synthesis or antagonize leukotriene receptors, which are as effective as cromolyn or theophylline, and may ↓ the amount of inhaled steroids needed to control inflammation See Asthma, Leukotrienes, Zafirlukast, Zileuton

Antileukotrienes

LTD₄ receptor antagonists

Zafirkulast-Accolate^® Benefits LTD₄-induced bronchoconstriction, early and late responses, exercise challenge, cold-induced asthma, chronic asthma

5-Lipoxygenase inhibitor

Zileutron-Zyflo^®Benefits asthma induced by exercise, cold, aspirin, bronchial hyperresponsiveness

FLAP inhibitors

None are FDA-approved Benefits early and late responses and cold-induced asthma

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