LHX1

(redirected from LIM homeobox protein 1)

LHX1

A gene on chromosome 17q12 that encodes a homeobox transcription factor which plays a key role in the development of the renal and urogenital systems.

Molecular pathology
LHX1 is a candidate gene for Mayer-Rokitansky-Kuster-Hauser syndrome, which is characterised by defects of the female genital tract.
References in periodicals archive ?
These changes correlated with down-regulation of effectors of differentiation [secreted frizzled-related sequence protein 1 (SJrpl), insulin-like growth factor 1 receptor (Igftr)> wingless-related MMTV-integration site 4 (Wnt4), Lim homeobox protein 1 (Lhxl), E-cadherin].