CDH17

(redirected from LI-cadherin)

CDH17

A gene on chromosome 8q22.1 that encodes cadherin 17, which is a component of the GI tract and pancreatic ducts, acting as an intestinal proton-dependent peptide transporter in the first step in oral absorption of medically important peptide-based drugs. Cadherin 17 may also play a role in the morphological organisation of the liver and intestine.
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Cadherin-17 (CDH17), also known as Li-cadherin (liverintestine cadherin), is a member of the cadherin superfamily and is a calcium-dependent transmembrane glycoprotein.
LI-cadherin gene expression during mouse intestinal development.