TMPO

(redirected from LEM domain containing 4)

TMPO

A gene on chromosome 12q22 that encodes thymopoietin, which may help direct nuclear lamina assembly and maintain the nuclear envelope’s structural organisation. Thymopoietin may act as a receptor for attachment of lamin filaments to the inner nuclear membrane.

Molecular pathology
Defects in TMPO cause cardiomyopathy dilated type 1.