LMNA

(redirected from LDP1)

LMNA

A gene on chromosome 1q22 that encodes lamin A/C, a protein highly conserved in evolution that forms part of the two-dimensional matrix of proteins located next to the inner nuclear membrane. Lamins are involved in providing nuclear stability and chromatin structure, and in gene expression.

Molecular pathology
LMNA mutations cause the so-called laminopathies—e.g., Charcot-Marie-Tooth disease type 2B1, progeria (Hutchinson-Gilford syndrome), dilated cardiomyopathy, Emery-Dreifuss muscular dystrophy type 2, familial partial lipodystrophy, limb-girdle muscular dystrophy type 1B, mandibuloacral dysplasia, and some cases of Werner syndrome.
References in periodicals archive ?
The report added: "Since LDP1 was withdrawn in March, work on preparing LDP2 has commenced.
33 N 3,308 1,431 631 253 Descriptive Statistics (Median) LDP1 JSP LDP2 DPJ Last margin 0.
New clonal types, such as LDP1, LDP2, PH1 and #777 are slowly being introduced by the Northern Mountainous Agriculture and Forestry Science Institute (formerly, Phu Ho Tea Research Institute) for higher yields, higher quality or improved adaptation to poor soil quality.