ERBB3

(redirected from LCCS2)

ERBB3

A gene on chromosome 12q13 that encodes a member of the epidermal growth factor receptor (EGFR) family of receptor tyrosine kinases which binds and is activated by neuregulins and NTAK.

Molecular pathology
ERBB3 amplification and overexpression has been described in multiple cancers, including prostate, bladder and breast.