l-iduronidase

l-iduronidase

/l-id·uron·i·dase/ (i″du-ron´ĭ-dās) a hydrolase that catalyzes a step in the degradation of the glycosaminoglycans dermatan sulfate and heparan sulfate; deficiency leads to mucopolysaccharidosis I.
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MPS I is a rare, progressive, heterogeneous, debilitating disease caused by a deficiency of the enzyme alpha L-iduronidase that affects an estimated 3,000 to 4,000 people worldwide, including approximately 1,000 in the United States.