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L-dopa |
Also found in: Dictionary/thesaurus, Encyclopedia, Wikipedia, Hutchinson | 0.07 sec. |
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l-dopa levodopa.
Levodopa (L-dopa) A substance used in the treatment of Parkinson's disease. Levodopa can cross the blood-brain barrier that protects the brain. Once in the brain, it is converted to dopamine and thus can replace the dopamine lost in Parkinson's disease. Mentioned in: Movement Disorders levodopa, L-DOPA the pharmaceutical name for dopa. |
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? Mentioned in | ? References in periodicals archive | |
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The trials covered Parkinson's disease patients with the wearing-off phenomenon, who have received the treatment with L-DOPA alone or L-DOPA with other agents. A number of studies simply stated diagnosis was confirmed by a neurologist, but most defined a case on the basis of the presence of two or more of the cardinal signs of PD (tremor, rigidity, brady-kinesia, and postural instability); some also used additional criteria, including responsiveness to L-dopa therapy and/or a progressive disorder. Subcortical vascular lesions predict functional recovery after rehabilitation in patients with L-dopa refractory parkinsonism. |
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